冠心病(Coronary Artery Disease,CAD)作为全球主要的致死性疾病之一,其病理机制涉及炎症、氧化应激、脂代谢紊乱及内皮功能障碍等。鸢尾素(Irisin)是一种由运动诱导的肌肉因子,近年来被发现与心血管疾病的发生发展密切相关。近年研究发现,鸢尾素可能通过多靶点参与冠心病的病理生理过程,为心血管疾病的防治提供了新思路。本文综述了鸢尾素的生物学特性及其通过调节代谢、抑制炎症反应、改善内皮功能等途径在冠心病中的作用,并探讨其作为新型生物标志物或治疗靶点的潜在价值。
冠心病;鸢尾素;生物标志物
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